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The Best Museums Across the Midwest

The Midwest is diverse and has unique attractions, from bustling cities to scenic small towns. Whether you’re taking a scenic drive through Wisconsin’s rolling hills, exploring the vibrant arts scene in Minneapolis, or enjoying the Great Lakes shoreline in Michigan, there’s something for everyone. That includes some really incredible museums in the Midwest, too!

One of the region’s best-kept secrets is its incredible selection of museums. You can discover world-renowned institutions like the Art Institute of Chicago, Illinois, or dive into fascinating hidden gems like the National Mississippi River Museum & Aquarium in Dubuque, Iowa. For history buffs, the Abraham Lincoln Presidential Library and Museum in Springfield, Illinois, is a must-see. Whether you’re into art, science, or history, the museums in the Midwest offer a range of experiences that rival those found in larger metropolitan areas, making it a perfect destination for curious minds.

You’ll find plenty of great ways to spend your time between museum visits. From local festivals and charming historic districts to exceptional restaurants and wineries, the Midwest is a diverse and fascinating part of the country to explore. Cap it all off with some of our world-famous Midwest hospitality, which offers travelers a warm, welcoming atmosphere everywhere they go. When it comes to places to stay in the Midwest, the last place you should consider looking are chain hotels. Instead, seek something unique for your vacation, and consider booking a stay at one of the region’s top-rated boutique inns, bed and breakfasts, or cabins.

From the luxurious properties in urban centers to the cozy cabins in rural countryside, there’s a perfect retreat for every type of traveler. Wherever your travels take you, you’ll find a comfortable and personalized experience. Let us be your guide to the best of the Midwest. Start by booking a stay at one of our unique lodging properties today! 

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Exterior of the Milwaukee Art Museums - one of the best museums in the Midwest
Mikwaukee Art Museum in Wisconsin

The Best Museums in the Midwest

There’s a surprising array of museums in the Midwest. Whether you’re an art lover, history buff, aviation enthusiast, or a fan of science and technology, there’s something worth seeing. Whether visiting major Midwest cities like Chicago or Milwaukee or embracing small-town charm in places like Winona, MN, or Ashland, NE, there are plenty of fantastic museums in the Midwest for every interest. 

States like Wisconsin, Minnesota, Iowa, Illinois, and Nebraska each offer unique cultural experiences through their museum collections. Whether you’re exploring Chicago’s world-class institutions or discovering smaller, lesser-known gems in rural areas, museums in the Midwest add depth to any getaway. Experiences range from interactive science centers to art galleries showcasing regional artists. Below, we’ve broken down a list of some of our favorite museums in the Midwest by state. We have curated a broad range of cultural experiences for curious travelers visiting our region.

Best Museums in Wisconsin

From the famed architecture and collection of the Milwaukee Art Museum to the breathtaking birds-in-art exhibit at Leigh Yawkey Woodson Art Museum in Wausau, there are so many exceptional museums in Wisconsin to visit. These no doubt represent some of the best museums in the Midwest. Our favorites are listed below.

  1. Milwaukee Art Museum is known for its stunning architecture and vast American and European art collection.
  2. The Harley-Davidson Museum in Milwaukee celebrates the history of this iconic motorcycle brand with bikes and memorabilia.
  3. The Madison Museum of Contemporary Art is a stunning hub for modern and contemporary works from around the world.
  4. Aviation enthusiasts, don’t miss the EAA Aviation Museum in Oshkosh. It features over 200 historic airplanes and interactive exhibits for aviation enthusiasts.
  5. The Chazen Museum of Art in Madison houses over 23,000 works of art spanning multiple genres and time periods.
  6. For something unique, head to the National Mustard Museum in Middleton. It’s a quirky gem with over 6,000 mustard varieties and fascinating mustard memorabilia.
  7. The Leigh Yawkey Woodson Art Museum in Wausau is home to the famed Birds in Art Exhibit each fall and winter. It is a must for nature lovers and art enthusiasts alike. 

Best Museums in Illinois

One of the most iconic museums in the Midwest is found in Chicago, but that’s just the start of the great museums you’ll find in Illinois. Below, we’ve listed some of the state’s best museums, including world-class art institutions and smaller hidden gems around the state. 

  1. The Art Institute of Chicago, one of the most iconic museums in the Midwest, is a world-class museum featuring works from ancient to modern times, including iconic pieces like “American Gothic.”
  2. The Field Museum, also in Chicago, is a renowned natural history museum with famous exhibits like the T. rex “Sue.”
  3. For science and technology fans, one of the best museums in the Midwest is the Griffin Museum of Science and Industry in Chicago. It features various hands-on exhibits on science, technology, and innovation, including a WWII submarine.
  4. Embrace history in Illinois at the Abraham Lincoln Presidential Library and Museum in Springfield. This Midwest museum offers immersive exhibits that pay tribute to Lincoln’s life and legacy.
  5. For another look at Illinois’ presidential history, head to the U.S. Grant Home and Museum in historic Galena. 
  6. The Richard H. Driehaus Museum in Chicago is a hidden gem that offers a glimpse into the Gilded Age through stunning interiors and decorative arts.
  7. Visit the Frank Lloyd Wright Home and Studio in Oak Park, where you can explore the iconic architect’s early work and his innovative designs.
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Inside view of the planes at one of the top Midwest museums in Nebraska
Strategic Air Command & Aerospace Museum in Nebraska

Best Museums in Minnesota

Though there are plenty of great museums in Minnesota’s largest cities, there are also several fantastic hidden gems around the state. 

  1. The Walker Art Center in Minneapolis is a leading contemporary art museum with dynamic exhibitions and a renowned sculpture garden.
  2. Minneapolis Institute of Art is another must when it comes to museums in the Midwest. It’s home to over 90,000 works of art from ancient to contemporary times.
  3. For something unique, head to Mill City Museum in Minneapolis. Housed in a historic flour mill, this museum tells the story of Minneapolis’ industrial past.
  4. The Bell Museum of Natural History in St. Paul is Minnesota’s official natural history museum. It features dioramas and a planetarium.
  5. Visit the American Swedish Institute in Minneapolis. This Midwest museum, housed in a beautiful mansion, focuses on Swedish culture and immigrant history.
  6. One of the best hidden gems among museums in Minnesota is the Minnesota Marine Art Museum in Winona. This incredible spot features stunning works of art inspired by water, including pieces by Monet and Van Gogh.
  7. For an insightful look at Minnesota’s unique cultural confluence, head to the National Hmong Museum in St. Paul. This cultural gem offers insight into Hmong history, traditions, and their journey to Minnesota.

Best Museums in Iowa

From stunning museums along the Mississippi River to exceptional glass, ceramic, and textile art, some truly exceptional museums in Iowa are worth visiting. We’ve listed a few of our favorites below! 

  1. The National Mississippi River Museum & Aquarium in Dubuque is a top-tier museum featuring river history, wildlife, and conservation.
  2. The Herbert Hoover Presidential Library and Museum in West Branch is dedicated to the life and legacy of the 31st U.S. President.
  3. The Des Moines Art Center is a contemporary art museum with exhibits ranging from modern to contemporary art.
  4. The Museum of Danish America in Elk Horn celebrates Danish heritage with cultural exhibits and artifacts.
  5. The Figge Art Museum in Davenport is known for its impressive collection of American, European, and contemporary works.
  6. The stunning Brunnier Art Museum in Ames specializes in decorative arts, featuring glass, ceramics, and textiles.

Best Museums in Nebraska

Finally, don’t miss the fascinating glimpse at history in America, not to mention exceptional science and technology and art museums in Nebraska. The state features several well-known institutions and plenty of unique hidden gems regarding museums in the Midwest. 

  1. The Strategic Air Command & Aerospace Museum in Ashland is one of the best museums in the Midwest for fans of aviation and technology. This museum features aircraft, space exhibits, and Cold War history.
  2. The Durham Museum in Omaha showcases local history and culture in a beautiful Art Deco train station.
  3. Sheldon Museum of Art in Lincoln is a hidden gem among museums in the Midwest. This incredible space features wonderful exhibits of American and contemporary art.
  4. Stuhr Museum of the Prairie Pioneer in Grand Island offers a living history experience of Nebraska’s pioneer days.
  5. For more American history, don’t miss Chimney Rock National Historic Site in Bayard. Here, you’ll find one of the best museums in Nebraska, dedicated to the famous landmark on the Oregon Trail.
  6. Another great spot to visit is The Archway in Kearney. This unique museum features interactive exhibits showcasing the westward expansion.
  7. Fan of cars and racing? Don’t miss the Museum of American Speed in Lincoln!
Couple staying at a Midwest Inn and planning their day at the top museums in the Midwest

The Best Places to Stay in the Midwest

Whether your goal is to visit as many museums in the Midwest as possible or to visit just one or two of these incredible institutions during your upcoming vacations, they will undoubtedly add plenty of depth and interest to your trip. They are, of course, just the tip of the iceberg when it comes to things to do in the Midwest. From grand adventures in the great outdoors and four seasons of exhilarating fun to exceptional restaurants and cultural attractions, the Midwest represents the best of America. While you’re exploring, let us take care of you with the best Midwestern hospitality around.

The Midwest Association of Independent Inns offers a collection of distinctive lodging options in diverse areas across states like Wisconsin, Minnesota, Illinois, Iowa, and Nebraska. These lodging properties range from traditional Bed and Breakfasts and historic Inns to cozy cabins and urban vacation rentals. Regardless of the accommodation type, all our unique lodging properties stand out from traditional hotels and provide unique experiences for travelers.

Above all else, these lodging properties offer more than just a place to rest—they are intimate settings perfect for romantic getaways and adventures across the Midwest. Their warm hospitality and personalized service make them an inviting alternative for couples and families seeking something special. Whether you’re exploring small towns or bustling cities, these Inns are the ideal base for discovering the best of the Midwest.

Each property offers its own charm, from historical homes to boutique bed and breakfasts, and are all licensed, inspected, and insured – an important peace of mind in today’s crowded lodging landscape. In addition to providing a safe, clean, and comfortable place to stay in the Midwest, our properties specialize in personalized care you can’t find anywhere else. Guests can enjoy luxurious accommodations with modern amenities while experiencing the authentic hospitality the Midwest is known for.

There’s little wonder why our properties are rated as the best places to stay in the Midwest. If you’re seeking a memorable, one-of-a-kind experience, look no further. Eschew the standard hotel room and unwind in the charm and comfort of our Midwest Inns and lodging properties. Book your Midwest getaway today! 

Lodging Properties near topics in our blog

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Sheridan’s Bed & Breakfast

  • 5133 South Lake Drive
    Cudahy, Wisconsin 53110
  • 414-747-9810
  • Email Us
This historic 1920’s building has been beautifully renovated and offers 8 private guest rooms, each named and styled after wine making regions.
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Whispering Pines Bed and Breakfast

  • 2018 6th Avenue
    Nebraska City, Nebraska 68410
  • 402-205-7003
  • Email Us
Offering 5 unique rooms with modern comforts amidst 1878 Victorian charm in Historic Southeast Nebraska. Featuring gourmet breakfasts, outdoor hot tub, fire pit, open air porch and pet-friendly rooms.
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Hotel Galena

  • 324 Spring Street
    Galena, Illinois 61036
  • 815-777-0123
  • Email Us
Located in historic downtown Galena, Hotel Galena offers a fabulous experience at an exceptional price. Boasting a 5* Google rating, it’s perfect for couples, families, groups, or solo travelers.
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Owl Ridge Cabin

  • 163554 Owl Ridge Road
    Wausau, Wisconsin 54403
  • 262-639-5500
  • Email Us
As the premiere vacation cabin in WI, Owl Ridge Cabin offers contemporary architecture with panoramic scenic views, a spa bathroom, gourmet kitchen & complete privacy. 10 minutes from downtown Wausau.
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Hotel Ruby Marie

  • 524 East Wilson Street
    Madison, Wisconsin 53703
  • 608-327-7829
  • Email Us
A renovated Victorian railroad inn in the heart of Madison, the Hotel Ruby Marie offers time-tested hospitality as well as convenient access to the modern life of Wisconsin’s capital city.
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The Muse Gallery Guesthouse

  • 602 East Lincoln Avenue
    Milwaukee, Wisconsin 53207
  • 414-745-7735
  • Email Us
The Muse Gallery Guesthouse is an art gallery inn in the heart of Bay View – Milwaukee’s, trendiest neighborhood. It is conveniently located near the Lake Express ferry port, airport, and downtown.
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The Three Elizabeths Guest House

  • 101 West Main Street
    Elizabeth, Illinois 61028
  • 815-990-8618
  • Email Us
Located 15 minutes East of Galena, accommodations include three Guest Rooms, classically styled, each with their own private bath. Reasonable rates and a welcoming front porch entice visitors.
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3rd Street Lofts

  • 615 N 3rd Street
    Wausau, Wisconsin 54403
  • (262) 639-5500
  • Email Us
Welcome to 3rd Street Lofts – located in the heart of downtown Wausau. Step out the door and explore the best shops, restaurants, theaters, museums, microbreweries, and distilleries Wausau offers.
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Stewart Inn

  • 521 Grant Street
    Wausau, Wisconsin 54403
  • 262-639-5500
  • Email Us
Rated a top 10 small stay property in the US (’21, ’22 & ’23), the Stewart Inn is an Arts & Crafts masterpiece offering luxury guest rooms, steam showers, 3 course breakfast & nightly wine reception.
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Historic District Bed and Breakfast

  • 483 Ashland Avenue
    Saint Paul, Minnesota 55102
  • 763-360-3717
  • Email Us
A high value boutique inn with a gourmet breakfast and personal service in a unique and historic neighborhood. Close to museums, concert venues, small business owned restaurants and bars.
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Cloran Mansion Bed & Breakfast

  • 1237 Franklin Street
    Galena, Illinois 61036
  • 815-777-0583
  • Email Us
Guests to the Cloran will find modern comfort surrounded by historic charm. Treat yourself to 21st-century amenities certain to pamper while taking in the beauty of 1800s Italianate architecture!
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Hawk Valley Retreat & Cottages

  • 2752 West Cording Road
    Galena, Illinois 61036
  • 815-777-4100
  • Email Us
You are invited to relax, restore, and explore at our Galena Illinois Bed and Breakfast, a nature lover’s destination. We are located just 8 miles east of downtown Galena, IL.
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WunderRoost Bed and Breakfast

  • 14817 South 25th Street
    Roca, Nebraska 68430
  • 402-430-9130
  • Email Us
Enjoy country life minutes from Lincoln and walking distance to a winery. Our new grain bin and our historic home are great ways to get away and see the stars and enjoy the outdoors.
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The Buckingham Inn

  • 1615 Summit Avenue
    Madison, Wisconsin 53726
  • 608-819-8029
  • Email Us
Dedicated to service and style near the UW-Madison campus, The Buckingham Inn features luxury guest suites and seasonal fresh breakfasts. Experience award-winning lodging in an award-winning city.
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Fisher House Bed & Breakfast

  • 407 5th Avenue South
    Clinton, Iowa 52732
  • 563-249-8948
  • Email Us
A completely remodeled Queen Anne Victorian home that features 4 unique bedrooms each with a private bathroom. There are 2 rooms with queen size beds and 2 rooms with king size beds.
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Como Lake Bed and Breakfast

  • 1205 West Como Boulevard
    Saint Paul, Minnesota 55103
  • 651-399-4111
  • Email Us
Classic Craftsman style Inn overlooking St Paul’s Como Lake and adjacent to the regional gem, Como Park.
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The Speckled Hen Inn

  • 5525 Portage Road
    Madison, Wisconsin 53704
  • 608-244-9368
  • Email Us
The Speckled Hen Inn is a farm-stay B&B and features uniquely different Guest Rooms, offering private baths with whirlpool jetted tubs and fireplaces. Close to everything yet feels miles away!
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